- Newly Discovered "Hybrid hepatocytes" Cells Regenerate Liver Tissue Without Forming Tumors. These cells proliferate and replenish liver mass after chronic liver injuries in mice. The new research study was published on August 13 in Cell, led by Dr. Michael Karin of the UCSD SRC - Project 1 [Image: Hybrid Hepatocytes (green) are found in the portal triad of a normal liver].
- Dr. Julian Schroeder, Project Leader of Superfund Project 7, distinguished professor of biology and co-director of UC San Diego Center for Food and Fuel for the 21st Century, was among five professors at UC San Diego recently elected to membership in the prestigious National Academy of Sciences, one of the highest honors bestowed on U.S. scientists and engineers. CONGRATULATIONS!!!
- Triclosan is an antimicrobial commonly found in soaps, shampoos, toothpastes and many other household items. Researchers at University of California, San Diego School of Medicine report potentially serious consequences of long-term exposure to the chemical. Triclosan causes liver fibrosis and cancer in laboratory mice through molecular mechanisms that are also relevant in humans. (Published Nov. 17 PNAS)
- Roots from Arabidopsis plants that accumulate metals bind to phytochelatins, which are engineered to fluoresce upon association with metals. This is an image from the research conducted within our Center led by Project Leader, Dr. Julian Schroeder.
- Members of our Community Engagement Core often visit communities that are exposed to land where the burning of trash and other man-made materials expose a risk to the people who live in the nearby communities.
- Researchers within our Center, UCSD and from Mexico, collaborate to address the environmental challenges in Los Laureles, a canyon that is home to 65,000 people in Tijuana and spills into the sensitive wetlands of the Tijuana Estuary in California.
- New UCSD Siliafluorene polymer sensor spray used to image trace TNT explosive particles left on a surface by someone who handled the explosive by fluorescence quenching. An exciting area of research led by, Dr. William Trogler.
- Scanning electron micrograph of Drosophila melanogaster that appeared on the cover of Science magazine (recorded by the UCSD SRP Imaging Core). Sestrins were shown to control ROS output and tissue damage.
- A solid terrain model our Center uses to locate toxicant hot spots in our study areas. This model represents a digital elevation model of land and sea floor for the Southern California-Northern Baja California region merging data from US and Mexico sources.
- UCSD's distinctive Geisel Library, is named for Theodor Seuss Geisel (better know as "Dr. Seuss") and is featured in UCSD's logo.
- This building is the home of the UCSD Superfund Research Center and provides a space for cutting-edge biomedical research. Funds for the building were provided by a gift from the Leichtag Family Foundation to provide some of UCSD's most talented scientists a space to make discoveries that will improve the health and well-being of the community.
- Map of Superfund sites in the contiguous United States. A Superfund site is an uncontrolled or abandoned place where hazardous waste is located, possibly affecting local ecosystems or people. Red indicates currently on National Priority List, yellow is proposed, green is deleted (usually meaning having been cleaned up) [Photo courtesy: US EPA - Superfund]
The objective of the UCSD Superfund Research Center (SRC) is to generate new perspectives on the molecular and genetic basis of the biological effects of toxicant exposure, leading to new methodologies for gauging health risks and assessing health effects; innovative detection and monitoring systems for toxicity; and novel models for bioremediation. Learn More
Newly Discovered Cells Regenerate Liver Tissue Without Forming Tumors. The study, published August 13 in Cell, is the first to identify these so-called “hybrid hepatocytes,” and show that they are able to regenerate liver tissue without giving rise to cancer.
Julian Schroeder, is among five professors at UC San Diego recently elected to membership in the prestigious National Academy of Sciences. Congratulations Julian!
Who are We?
UCSD Superfund Research Center
University of California, San Diego
9500 Gilman Drive, Mail code 0722
La Jolla, CA 92093-0722