Superfund Basic Research Program

UCSD SBRP scientist co-discovers how particular genetic mutations affect autism spectrum disorder

Research of Palmer Taylor, SBRP PI, is published as the cover article in the June 2007 issue of the journal Structure

As a result of mapping the structure of the protein complex implicated in autism spectrum disorders, a research team led by scientists at the University of California, San Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences has discovered how particular genetic mutations affect this complex and contribute to the developmental abnormalities found in children with autism. Their work, published as the cover article in the June issue of the journal Structure, should help scientists pinpoint the consequences of other genetic abnormalities associated with the disorder. Learn more

Media Contact: Debra Kain, 619-543-6163

Also see: Fabrichny IP, Leone P, Sulzenbacher G, Comoletti D, Miller MT, Taylor P, Bourne Y, Marchot PStructural Analysis of the Synaptic Protein Neuroligin and Its beta-Neurexin Complex: Determinants for Folding and Cell AdhesionNeuron v56, p.979-991 http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?uid=61716

11/16 at 01:08 AM in Research Projects • Project 6 • Research Support Cores • Training Core • (0) Comments