Superfund Publications

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PubMed Central ID: 

Falivelli, G., De Jaco, A., Favaloro, F. L., Kim, H., Wilson, J., Dubi, N., Ellisman, M. H., Abrahams, B. S., Taylor, P., Comoletti, D. (2012) Inherited genetic variants in autism-related CNTNAP2 show perturbed trafficking and ATF6 activation. Hum Mol Genet. 21(21), 4761-73.

PubMedID: 22872700
PubMed Central ID: 

Pohaku Mitchell, K. K., Liberman, A., Kummel, A. C., Trogler, W. C. (2012) Iron(III)-doped, silica nanoshells: a biodegradable form of silica. J Am Chem Soc. 134(34), 13997-4003.

PubMedID: 22871140
PubMed Central ID: 

Breen, K. M., Thackray, V. G., Hsu, T., Mak-McCully, R. A., Coss, D., Mellon, P. L. (2012) Stress levels of glucocorticoids inhibit LHβ-subunit gene expression in gonadotrope cells. Mol. Endocrinol. 26(10), 1716-31.

PubMedID: 22851703
PubMed Central ID: 

Witham, E. A., Meadows, J. D., Shojaei, S., Kauffman, A. S., Mellon, P. L. (2012) Prenatal exposure to low levels of androgen accelerates female puberty onset and reproductive senescence in mice. Endocrinology. 153(9), 4522-32.

PubMedID: 22778229
PubMed Central ID: 

Witham, E. A., Meadows, J. D., Shojaei, S., Kauffman, A. S., Mellon, P. L. (2012) Prenatal exposure to low levels of androgen accelerates female puberty onset and reproductive senescence in mice. Endocrinology. 153(9), 4522-32.

PubMedID: 22778229
PubMed Central ID: 

Yueh, M. F., Li, T., Evans, R. M., Hammock, B., Tukey, R. H. (2012) Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive androstane receptor and the estrogen receptor alpha. PLoS One7(6):e37705. doi: 10.1371/journal.pone.0037705.

PubMedID: 22761658
PubMed Central ID: 

Seki, E., Brenner, D. A., Karin, M. (2012) A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. Gastroenterology. 143(2), 307-20. doi: 10.1053/j.gastro.2012.06.004.

PubMedID: 22705006

Font-Burgada, J., Seki, E., Karin, M. (2012) CYLD and HCC: when being too sensitive to your dirty neighbors results in self-destruction. Cancer Cell. 21(6), 711-2

PubMedID: 22698394
PubMed Central ID: 

Font-Burgada, J., Seki, E., Karin, M. (2012) CYLD and HCC: when being too sensitive to your dirty neighbors results in self-destruction. Cancer Cell. 21(6), 711-2. doi: 10.1016/j.ccr.2012.05.034.

PubMedID: 22698394

Font-Burgada, J., Seki, E., Karin, M. (2012) CYLD and HCC: when being too sensitive to your dirty neighbors results in self-destruction. Cancer Cell. 21(6), 711-2.

PubMedID: 22698394
PubMed Central ID: 

Guo, L., Ghassemian, M., Komives, E. A., Russell, P. (2012) Cadmium-induced proteome remodeling regulated by Spc1/Sty1 and Zip1 in fission yeast. Toxicol Sci. 129(1), 200-12.

PubMedID: 22610605

 Abe, Y., Uchinami, H., Kudoh, K., Nakagawa, Y., Ise, N., Watanabe, G., Sato, T., Seki, E., Yamamoto, Y. (2012)  Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expression of HIF-1 alpha target genes. Surgery. 152(5), 869-78.

PubMedID: 22575885
PubMed Central ID: 

Fan, W., Downes, M., Atkins, A., Yu, R., Evans, R. M. (2011) Nuclear receptors and AMPK: resetting metabolism. Cold Spring Harb Symp Quant Biol. 76:17-22. doi: 10.1101/sqb.2012.76.010470.

PubMedID: 22411605
PubMed Central ID: 

Chen, S., Yueh, M. F., Evans, R. M., Tukey, R. H. (2012) Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice. Hepatology. 56(2):658-67. doi: 10.1002/hep.25671.

PubMedID: 22371261
PubMed Central ID: 

Noreault-Conti, T. L., Fellows, A., Jacobs, J. M., Trask, H. W., Strom, S. C., Evans, R. M., Wrighton, S. A., Sinclair, P. R., Sinclair, J. F., Nichols, R. C. (2012) Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes. Int Immunopharmacol. 12(4):651-6. doi: 10.1016/j.intimp.2012.01.008.

PubMedID: 22310326
PubMed Central ID: 

Ghochani, Y., Saini, J. K., Mellon, P. L., Thackray, V. G. (2012) FOXL2 is involved in the synergy between activin and progestins on the follicle-stimulating hormone β-subunit promoter. Endocrinology. 153(4), 2023-33.

PubMedID: 22294749
PubMed Central ID: 

Jobe, T. O., Sung, D. Y., Akmakjian, G., Pham, A., Komives, E. A., Mendoza-Cózatl, D. G., Schroeder, J. I. (2012) Feedback inhibition by thiols outranks glutathione depletion: a luciferase-based screen reveals glutathione-deficient γ-ECS and glutathione synthetase mutants impaired in cadmium-induced sulfate assimilation. Plant J. 70(5), 783-95. doi: 10.1111/j.1365-313X.2012.04924.x.

PubMedID: 22283708

Jobe, T. O., Sung, D. Y., Akmakjian, G., Pham, A., Komives, E. A., Mendoza-Cózatl, D. G., Schroeder, J. I. (2012) Feedback inhibition by thiols outranks glutathione depletion: a luciferase-based screen reveals glutathione-deficient γ-ECS and glutathione synthetase mutants impaired in cadmium-induced sulfate assimilation. Plant J. 70(5), 783-95.

PubMedID: 22283708
PubMed Central ID: 

Sun, B., Karin, M. (2012) Obesity, inflammation, and liver cancer. J Hepatol. 56(3), 704-13. doi: 10.1016/j.jhep.2011.09.020.

PubMedID: 22120206
PubMed Central ID: 

Brayman, M. J., Pepa, P. A., Berdy, S. E., Mellon, P. L. (2012) Androgen receptor repression of GnRH gene transcription. Mol. Endocrinol. 26(1), 2-13.

PubMedID: 22074952
PubMed Central ID: 

Brayman, M. J., Pepa, P. A., Berdy, S. E., Mellon, P. L. (2012) Androgen receptor repression of GnRH gene transcription. Mol. Endocrinol. 26(1), 2-13.

PubMedID: 22074952
PubMed Central ID: 

Fujiwara, R., Chen, S., Karin, M., Tukey, R. H. (2012) Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia. Gastroenterology. 142(1), 109-118.

PubMedID: 21983082
PubMed Central ID: 

Fujiwara, R., Chen, S., Karin, M., Tukey, R.H. (2012) Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia. Gastroenterology. 142(1), 109-118. doi: 10.1053/j.gastro.2011.09.045.

PubMedID: 21983082
PubMed Central ID: 

Fujiwara, R., Chen, S., Karin, M., Tukey, R. H. (2012) Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia. Gastroenterology. 142(1), 109-118.

PubMedID: 21983082
PubMed Central ID: 

Holzer, R. G., Park, E. J., Li, N., Tran, H., Chen, M., Choi, C., Solinas, G., Karin, M. (2011) Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation. Cell. 147(1), 173-84. doi: 10.1016/j.cell.2011.08.034.

PubMedID: 21962514
PubMed Central ID: 

Xue, S., Yao, X., Luo, W., Jha, D., Tester, M., Horie, T., Schroeder, J. I. (2011) AtHKT1;1 mediates nernstian sodium channel transport properties in Arabidopsis root stelar cells. PLoS One. 6(9):e24725. doi: 10.1371/journal.pone.0024725.

PubMedID: 21931830
PubMed Central ID: 

Mendoza-Cózatl, D.G., Jobe, T. O., Hauser, F., Schroeder, J. I. (2011) Long-distance transport, vacuolar sequestration, tolerance, and transcriptional responses induced by cadmium and arsenic. Curr Opin Plant Biol. 14(5), 554-62. doi: 10.1016/j.pbi.2011.07.004.

PubMedID: 21820943
PubMed Central ID: 

Rodríguez-Gabriel, M. A., Russell, P. (2008) Control of mRNA stability by SAPKs. Top Curr Genet. 20, 159-170.

PubMedID: 21738496
PubMed Central ID: 

Jannat, R., Uraji, M., Morofuji, M., Islam, M. M., Bloom, R. E., Nakamura, Y., McClung, C. R., Schroeder, J. I., Mori, I. C., Murata, Y. (2011) Roles of intracellular hydrogen peroxide accumulation in abscisic acid signaling in Arabidopsis guard cells. J Plant Physiol. 168(16),1919-26. doi: 10.1016/j.jplph.2011.05.006.

PubMedID: 21665322
PubMed Central ID: 

Horie, T., Brodsky, D. E., Costa, A., Kaneko, T., Lo Schiavo, F., Katsuhara, M., Schroeder, J. I. (2011) K+ transport by the OsHKT2;4 transporter from rice with atypical Na+ transport properties and competition in permeation of K+ over Mg2+ and Ca2+ ions. Plant Physiol. 156(3), 1493-507. doi: 10.1104/pp.110.168047.

PubMedID: 21610181
PubMed Central ID: 

​Hauser, F. Waadt, R. & Schroeder, J. I. (2011) Evolution of abscisic acid synthesis and signaling mechanisms. Curr Biol. doi: 10.1016/j.cub.2011.03.015.

PubMedID: 21549957
PubMed Central ID: 

Kacevska, M., Downes, M. R., Sharma, R., Evans, R. M., Clarke, S. J., Liddle, C., Robertson, G. R. (2011) Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism. Clin Cancer Res. 17(10):3170-80. doi: 10.1158/1078-0432.CCR-10-3289.

PubMedID: 21498392
PubMed Central ID: 

Böhmer, M. & Schroeder, J. I. (2011) Quantitative transcriptomic analysis of ABA-induced and ROSdependent expression changes and proteomic profiling in Arabidopsis suspension cells. Plant Journal. 67(1):105-18. doi: 10.1111/j.1365-313X.2011.04579.x. 

PubMedID: 21426425
PubMed Central ID: 

Yueh, M. F., Mellon, P. L., Tukey, R. H. (2011) Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane receptor. Mol Pharmacol. 79(6),1053-60. doi: 10.1124/mol.110.070649.

PubMedID: 21415305
PubMed Central ID: 

Larder, R., Clark, D. D., Miller, N. L., Mellon, P. L. (2011) Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6. J. Neurosci. 31(2), 426-38.

PubMedID: 21228153
PubMed Central ID: 

Österreicher, C.H., Penz-Österreicher, M., Grivennikov, S. I., Guma, M., Koltsova, E. K., Datz, C., Sasik, R., Hardiman, G., Karin, M., Brenner, D. A. (2011) Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver. Proc. Natl. Acad. Sci. USA. 108(1), 308-13.

PubMedID: 21173249
PubMed Central ID: 

Österreicher, C.H., Penz-Österreicher, M., Grivennikov, S. I., Guma, M., Koltsova, E. K., Datz, C., Sasik, R., Hardiman, G., Karin, M., Brenner, D. A., (2011) Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver. Proc Natl Acad Sci USA. 108(1), 308-13. doi: 10.1073/pnas.1017547108.

PubMedID: 21173249
PubMed Central ID: 

Österreicher, C. H., Penz-Österreicher, M., Grivennikov, S. I., Guma, M., Koltsova, E. K., Datz, C., Sasik, R., Hardiman, G., Karin, M., Brenner, D. A. (2011) Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver. Proc Natl Acad Sci USA. 108(1), 308-13.

PubMedID: 21173249
PubMed Central ID: 

Suhr, S. T., Chang, E. A., Tjong, J., Alcasid, N., Perkins, G. A., Goissis, M. D., Ellisman, M. H., Perez, G. I., Cibelli, J. B. (2010) Mitochondrial rejuvenation after induced pluripotency. PLoS One. doi: 10.1371/journal.pone.0014095.

PubMedID: 21124794
PubMed Central ID: 

Song, W. Y., Park, J., Mendoza-Cózatl, D.G., Suter-Grotemeyer, M., Shim, D., Hörtensteiner, S., Geisler, M., Weder, B., Rea, P. A., Rentsch, D., Schroeder, J. I., Lee, Y., Martinoia, E. (2010) Arsenic tolerance in Arabidopsis is mediated by two ABCC-type phytochelatin transporters. Proc Natl Acad Sci USA. 107, 21187-92. doi: 10.1073/pnas.1013964107.

PubMedID: 21078981
PubMed Central ID: 

Mendoza-Cozatl, D., Zhai, Z., Jobe, T., G.Z., A., Song, W. Y., Limbo, O., Russell, M., Kozlovskyy, V., Martinoia, E., Vatamaniuk, O. K., Russell, P., Schroeder, J. I. (2010) Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance. J Biol Chem. 285, 40416-40426.

PubMedID: 20937798
PubMed Central ID: 

Mendoza-Cózatl, D. G., Zhai, Z, Jobe, T. O., Akmakjian, G. Z., Song, W. Y., Limbo, O., Russell, M. R., Kozlovskyy, V. I., Martinoia, E., Vatamaniuk, O. K., Russell, P., Schroeder, J. I. (2010) Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance. J Biol Chem. 285(52), 40416-26. doi: 10.1074/jbc.M110.155408.

PubMedID: 20937798
PubMed Central ID: 

Budanov, A. V., Lee, J. H., Karin, M. (2010) Stressin' Sestrins take an aging fight. E. M. B. O. Mol. Med. 2(10), 388-400.

PubMedID: 20878915
PubMed Central ID: 

Budanov, A. V., Lee, J. H., Karin, M. (2010) Stressin' sestrins take an aging fight. EMBO Mol Med. 2(10), 388-400. doi: 10.1002/emmm.201000097.

PubMedID: 20878915
PubMed Central ID: 
Comoletti, D., Miller, M. T., Jeffries, C. M., Wilson, J., Demeler, B., Taylor, P., Trewhella, J., Nakagawa, T. (2010) The macromolecular architecture of extracellular domain of alphaNRXN1: domain organization, flexibility, and insights into trans-synaptic disposition. Structure. 18(8), 1044-53. 
PubMedID: 20696403
PubMed Central ID: 

Lamia, K. A., Evans, R. M. (2010) Metabolism: Tick, tock, a beta-cell clock. Nature. 466(7306):571-2. doi: 10.1038/466571a.

PubMedID: 20671699
PubMed Central ID: 

De Jaco, A., Lin, M. Z., Dubi, N., Comoletti, D., Miller, M. T., Camp, S., Ellisman, M., Butko, M. T., Tsien, R. Y., Taylor, P. (2010) Neuroligin trafficking deficiencies arising from mutations in the alpha/beta-hydrolase fold protein family. J Biol Chem. 285(37), 28674-82.

PubMedID: 20615874
PubMed Central ID: 

Lee, J. H., Bodmer, R., Bier, E., Karin, M. (2010) Sestrins at the crossroad between stress and aging. Aging (Albany NY). 2(6), 369-74.

PubMedID: 20606249
PubMed Central ID: 

Lee, J. H., Bodmer, R., Bier, E., Karin, M. (2010) Sestrins at the crossroad between stress and aging. Aging (Albany NY). 2(6), 369-74. doi: 10.18632/aging.100157

PubMedID: 20606249
PubMed Central ID: 

Li, J-Y., Fu, Y-L., Pike, S.M., Bao, J., Tian, W., Zhang, Y., Chen, C-Z., Zhang, Y., Li, H-M., Huang, J., Li, L-G., Schroeder, J.I., Gassmann, W., Gong, J-M. The Arabidopsis nitrate transporter NRT1.8 functions in nitrate removal from the xylem and mediates cadmium tolerance. Plant Cell 22: 1633-46 (2010).

PubMedID: 20501909

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