Superfund Publications

Search publications on site
PubMed Central ID: 
Liberman, A., Mendez, N., Trogler, W. C., Kummel, A.C. (2014) Synthesis and surface functionalization of silica nanoparticles for nanomedicine. Surf Sci Rep. 69(2-3), 132-158.
PubMedID: 25364083
PubMed Central ID: 

Al-Delaimy, W. K., Larsen, C. W., Pezzoli, K. (2014) Differences in health symptoms among residents living near illegal dump sites in Los Laureles Canyon, Tijuana, Mexico: a cross sectional survey. In.t J. Environ. Res. Public Health. 11(9), 9532-52.

PubMedID: 25226411
PubMed Central ID: 

Ahow, M., Min, L., Pampillo, M., Nash, C., Wen, J., Soltis, K., Carroll, R. S., Glidewell-Kenney, C. A., Mellon, P. L., Bhattacharya, M., Tobet, S. A., Kaiser, U. B., Babwah, A.V. (2014) KISS1R Signals Independently of Gαq/11 and Triggers LH Secretion via the β-Arrestin Pathway in the Male Mouse. Endocrinology. 155(11), 4433-46.

PubMedID: 25147978
PubMed Central ID: 

Suh, J. M., Jonker, J. W., Ahmadian, M., Goetz, R., Lackey, D., Osborn, O., Huang, Z., Liu, W., Yoshihara, E., van Dijk, T. H., Havinga, R., Fan, W., Yin, Y. Q., Yu, R. T., Liddle, C., Atkins, A. R., Olefsky, J. M., Mohammadi, M., Downes, M., Evans, R. M. (2014) Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature. doi: 10.1038/nature13540.

PubMedID: 25043058
PubMed Central ID: 

Sherman, M. H., Yu, R. T., Engle, D. D., Ding, N., Atkins, A. R., Tiriac, H., Collisson, E. A., Connor, F., Van Dyke, T., Kozlov, S., Martin, P., Tseng, T. W., Dawson, D. W., Donahue, T. R., Masamune, A., Shimosegawa, T., Apte, M. V., Wilson, J. S., Ng, B., Lau, S. L., Gunton, J. E., Wahl, G. M., Hunter, T., Drebin, J. A., O'Dwyer, P. J., Liddle, C., Tuveson, D. A., Downes, M., Evans, R. M. (2014) Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy. Cell. 159, 80-93.

PubMedID: 25259922
PubMed Central ID: 

Nakagawa, H., Umemura, A., Taniguchi, K., Font-Burgada, J., Dhar, D., Ogata, H., Zhong, Z., Valasek, M. A., Seki, E., Hidalgo, J., Koike, K., Kaufman, R. J., Karin, M. (2014) ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. Cancer Cell. 26(3), 331-43.

PubMedID: 25132496
PubMed Central ID: 
Hoffmann, H. M., Tamrazian, A., Xie, H., Pérez-Millán, M. I., Kauffman, A. S., Mellon, P. L. (2014) Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice. Endocrinology. 155(10), 4043-53.
PubMedID: 25060364
PubMed Central ID: 

Glidewell-Kenney, C. A., Trang, C., Shao, P. P., Gutierrez-Reed, N., Uzo-Okereke, A. M., Coss, D., Mellon, P. L. (2014) Neurokinin B induces c-fos transcription via protein kinase C and activation of serum response factor and Elk-1 in immortalized GnRH neurons. Endocrinology. 155(10), 3909-19.

PubMedID: 25057795
PubMed Central ID: 

Dowding, J. M., Song, W., Bossy, K., Karakoti, A., Kumar, A., Kim, A., Bossy, B., Seal, S., Ellisman, M. H., Perkins, G., Self, W. T., Bossy-Wetzel, E. (2014) Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell death. Cell Death. Differ. 21(10), 1622-32.

PubMedID: 24902900
PubMed Central ID: 

Mendoza-Cózatl, D.G., Xie, Q., Akmakjian, G. Z., Jobe, T. O., Patel, A., Stacey, M. G., Song, L., Demoin, D. W., Jurisson, S. S., Stacey, G., Schroeder, J. I. (2014) OPT3 is a component of the iron-signaling network between leaves and roots and misregulation of OPT3 leads to an over-accumulation of cadmium in seeds. Mol Plant. 7(9), 1455-69.

PubMedID: 24880337
PubMed Central ID: 

Maruo, Y., Morioka, Y., Fujito, H., Nakahara, S., Yanagi, T., Matsui, K., Mori, A., Sato, H., Tukey, R. H., Takeuchi, Y. (2014) Bilirubin Uridine Diphosphate-Glucuronosyltransferase Variation Is a Genetic Basis of Breast Milk Jaundice. J Pediatr. doi: 10.1016/j.jpeds.2014.01.060.

PubMedID: 24650397
PubMed Central ID: 

Inokuchi-Shimizu, S., Park, E. J., Roh, Y. S., Yang, L., Zhang, B., Song, J., Liang, S., Pimienta, M., Taniguchi, K., Wu, X., Asahina, K., Lagakos, W., Mackey, M. R., Akira, S., Ellisman, M. H., Sears, D. D., Olefsky, J. M., Karin, M., Brenner, D. A., Seki, E. (2014) ETAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. J Clin Invest. 124(8), 3566-78.

PubMedID: 24983318
PubMed Central ID: 

Lopez-Sanchez, I., Dunkel, Y., Roh, Y. S., Mittal, Y., De Minicis, S., Muranyi, A., Singh, S., Shanmugam, K., Aroonsakool, N., Murray, F., Ho, S. B., Seki, E., Brenner, D. A., Ghosh, P. (2014) GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis. Nat Commun. 5, 4451.

PubMedID: 25043713
PubMed Central ID: 

Jannat, R., Uraji, M., Morofuji, M., Islam, M. M., Bloom, R. E., Nakamura, Y., McClung, C. R., Schroeder, J. I., Mori, I. C., Murata, Y. (2011) Roles of intracellular hydrogen peroxide accumulation in abscisic acid signaling in Arabidopsis guard cells. J Plant Physiol. 168(16),1919-26.

PubMedID: 21665322
PubMed Central ID: 
Stephan, A. B., Schroeder, J. I. (2014) Plant salt stress status is transmitted systemically via propagating calcium waves.
Proc Natl Acad Sci U S A. 111(17), 6126-7.
PubMedID: 24737890
PubMed Central ID: 
Waadt, R., Hitomi, K., Nishimura, N., Hitomi, C., Adams, S. R., Getzoff, E. D., Schroeder, J. I. (2014) FRET-based reporters for the direct visualization of abscisic acid concentration changes and distribution in Arabidopsis.
Elife. 3, e01739.
PubMedID: 24737861
PubMed Central ID: 

Hong, S. H., Ahmadian, M., Yu, R. T., Atkins, A. R., Downes, M., Evans, R. M. (2014) Nuclear receptors and metabolism: from feast to famine. Diabetologia. 57(5), 860-7.

PubMedID: 24619218
PubMed Central ID: 

Schroeder, J. I., Delhaize, E., Frommer, W. B., Guerinot, M. L., Harrison, M. J., Herrera-Estrella, L., Horie, T., Kochian, L. V., Munns, R., Nishizawa, N. K., Tsay, Y. F., Sanders, D. (2013) Using membrane transporters to improve crops for sustainable food production. Nature. 497(7447), 60-6.

PubMedID: 23636397
PubMed Central ID: 

Dhar, D., Seki, E., Karin, M. (2014) NCOA5, IL-6, type 2 diabetes, and HCC: The deadly quartet. Cell Metab. 19(1), 6-7.

PubMedID: 24411937
PubMed Central ID: 

Ahmadian, M., Suh, J. M., Hah, N., Liddle, C., Atkins, A. R., Downes, M., Evans, R. M. (2013) PPARγ signaling and metabolism: the good, the bad and the future. Nat Med. 19(5), 557-66.

PubMedID: 23652116
PubMed Central ID: 

Fan, W., Downes, M., Atkins, A., Yu, R., Evans, R. M. (2011) Nuclear receptors and AMPK: resetting metabolism. Cold Spring Harb Symp Quant Biol. 76, 17-22.

PubMedID: 22411605
PubMed Central ID: 

Sumida, K., Kawana, M., Kouno, E., Itoh, T., Takano, S., Narawa, T., Tukey, R. H., Fujiwara, R. (2013) Importance of UDP-glucuronosyltransferase 1A1 expression in skin and its induction by UVB in neonatal hyperbilirubinemia. Mol Pharmacol. 84, 679-686.

PubMedID: 23950218
PubMed Central ID: 

Shibuya, A., Itoh, T., Tukey, R. H., Fujiwara, R. (2013)  Impact of fatty acids on human UDP-glucuronosyltransferase 1A1 activity and its expression in neonatal hyperbilirubinemia. Sci Rep. doi: 10.1038/srep02903.

 

PubMedID: 24104695
PubMed Central ID: 

Larder, R., Kimura, I., Meadows, J., Clark, D. D., Mayo, S., Mellon, P. L. (2013) Gene dosage of Otx2 is important for fertility in male mice. Mol. Cell. Endocrinol. 377(1-2), 16-22.

PubMedID: 23811236
PubMed Central ID: 

Lee, J. H., Budanov, A. V., Talukdar, S., Park, E. J., Park, H. L., Park, H. W., Bandyopadhyay, G., Li, N., Aghajan, M., Jang, I., Wolfe, A. M., Perkins, G. A., Ellisman, M., Bier, E., Scadeng, M., Foretz, M., Viollet, B., Olefsky, J., Karin, M. (2012) Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3. Cell Metab.16(3), 311-21.

PubMedID: 22958918
PubMed Central ID: 

Uhlenhaut, N. H., Barish, G. D., Yu, R. T., Downes, M., Karunasiri, M., Liddle, C., Schwalie, P., Hübner, N., Evans, R. M. (2013) Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes. Mol Cell. 49(1), 158-71.

PubMedID: 23159735
PubMed Central ID: 

Glidewell-Kenney, C. A., Shao, P. P., Iyer, A. K., Grove, A. M., Meadows, J. D., Mellon, P. L. (2013) Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neurons. Mol. Endocrinol. 27(3), 437-54.

PubMedID: 23393128
PubMed Central ID: 

Clark, D. D., Gorman, M. R., Hatori, M., Meadows, J. D., Panda, S., Mellon, P. L. (2013) Aberrant development of the suprachiasmatic nucleus and circadian rhythms in mice lacking the homeodomain protein Six6. J. Biol. Rhythms. 28(1), 15-25.

PubMedID: 23382588
PubMed Central ID: 

Seki, E., Brenner, D. A., Karin, M. (2012) A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. Gastroenterology. 143(2), 307-20.

PubMedID: 22705006
PubMed Central ID: 

Breen, K. M., Thackray, V. G., Hsu, T., Mak-McCully, R. A., Coss, D., Mellon, P. L. (2012) Stress levels of glucocorticoids inhibit LHβ-subunit gene expression in gonadotrope cells. Mol. Endocrinol. 26(10), 1716-31.

PubMedID: 22851703
PubMed Central ID: 

Fujiwara, R., Chen, S., Karin, M., Tukey, R. H. (2012) Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia. Gastroenterology. 142(1), 109-118.

PubMedID: 21983082
PubMed Central ID: 

Chen, S., Yueh, M. F., Evans, R. M., Tukey, R. H. (2012) Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice. Hepatology. 56, 658-667.

PubMedID: 22371261
PubMed Central ID: 

Ghochani, Y., Saini, J. K., Mellon, P. L., Thackray, V. G. (2012) FOXL2 is involved in the synergy between activin and progestins on the follicle-stimulating hormone β-subunit promoter. Endocrinology. 153(4), 2023-33.

PubMedID: 22294749
PubMed Central ID: 

Holzer, R. G., Park, E. J., Li, N., Tran, H., Chen, M., Choi, C., Solinas, G., Karin, M. (2011) Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation. Cell. 147(1), 173-84

PubMedID: 21962514
PubMed Central ID: 

Brayman, M. J., Pepa, P. A., Berdy, S. E., Mellon, P. L. (2012) Androgen receptor repression of GnRH gene transcription. Mol. Endocrinol. 26(1), 2-13.

PubMedID: 22074952
PubMed Central ID: 

Budanov, A. V., Lee, J. H., Karin, M. (2010) Stressin' sestrins take an aging fight. EMBO Mol Med. 2(10), 388-400.

PubMedID: 20878915
PubMed Central ID: 

​Hauser, F. Waadt, R. & Schroeder, J. I. (2011) Evolution of abscisic acid synthesis and signaling mechanisms. Curr Biol. doi: 10.1016/j.cub.2011.03.015.

PubMedID: 21549957
PubMed Central ID: 

Yueh, M. F., Mellon, P. L., Tukey, R. H. (2011) Inhibition of human UGT2B7 gene expression in transgenic mice by the constitutive androstane receptor. Mol Pharmacol. 79(6),1053-60.

PubMedID: 21415305
PubMed Central ID: 

Kim, T. H., Bohmer, M., Hu, H., Nishimura, N., Schroeder, J. I. (2010) Guard cell signal transduction network: advances in understanding Abscisic acid, CO2, and Ca2+ signaling. Annual Review of Plant Biology. 61, 561-91.

PubMedID: 20192751
PubMed Central ID: 

Österreicher, C. H., Penz-Österreicher, M., Grivennikov, S. I., Guma, M., Koltsova, E. K., Datz, C., Sasik, R., Hardiman, G., Karin, M., Brenner, D. A. (2011) Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver. Proc Natl Acad Sci USA. 108(1), 308-13.

PubMedID: 21173249
PubMed Central ID: 

Mendoza-Cozatl, D., Zhai, Z., Jobe, T., G.Z., A., Song, W. Y., Limbo, O., Russell, M., Kozlovskyy, V., Martinoia, E., Vatamaniuk, O. K., Russell, P., Schroeder, J. I. (2010) Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance. J Biol Chem. 285, 40416-40426.

PubMedID: 20937798
PubMed Central ID: 
Comoletti, D., Miller, M. T., Jeffries, C. M., Wilson, J., Demeler, B., Taylor, P., Trewhella, J., Nakagawa, T. (2010) The macromolecular architecture of extracellular domain of alphaNRXN1: domain organization, flexibility, and insights into trans-synaptic disposition. Structure. 18(8), 1044-53. 
PubMedID: 20696403
PubMed Central ID: 

De Jaco, A., Lin, M. Z., Dubi, N., Comoletti, D., Miller, M. T., Camp, S., Ellisman, M., Butko, M. T., Tsien, R. Y., Taylor, P. (2010) Neuroligin trafficking deficiencies arising from mutations in the alpha/beta-hydrolase fold protein family. J Biol Chem. 285(37), 28674-82.

PubMedID: 20615874
PubMed Central ID: 

Rodriguez-Gabriel, M. A., Russell, P. (2008) Control of mRNA stability by SAPKs. Topics Curr Genet. 20, 50-166.

PubMedID: 14633985
PubMed Central ID: 

Li, J-Y., Fu, Y-L., Pike, S.M., Bao, J., Tian, W., Zhang, Y., Chen, C-Z., Zhang, Y., Li, H-M., Huang, J., Li, L-G., Schroeder, J.I., Gassmann, W., Gong, J-M. The Arabidopsis nitrate transporter NRT1.8 functions in nitrate removal from the xylem and mediates cadmium tolerance. Plant Cell 22: 1633-46 (2010).

PubMedID: 20501909
PubMed Central ID: 

Argikar, U.A., Senekeo-Effenberger, K., Larson, E.E., Tukey, R.H., Remmel, R.P. (2009) Studies on induction of lamotrigine metabolism in transgenic UGT1 mice. Xenobiotica. 39, 826-835.

PubMedID: 19845433
PubMed Central ID: 

Costa, A., Drago, I., Behera, S., Zottini, M., Pizzo, P., Schroeder, J. I., Pozzan, T., Schiavao, F. L. (2010) H(2)O(2) in plant peroxisomes: an in vivo analysis uncovers a Ca(2+)-dependent scavenging system. Plant J. 62(5), 760-772.

PubMedID: 20230493
PubMed Central ID: 

Pyo, Y.J., Gierth, M., Schroeder, J.I., Cho, M.H. (2010) High-affinity K+ transport in Arabidopsis: AtHAK5 and AKT1 are vital for seedling establishment and postgermination growth under low-potassium conditions. Plant Physiol. 153, 863-75.

PubMedID: 20413648
PubMed Central ID: 

Cai, H., Nguyen, N., Peterkin, V., Young-Sun, Y., Hotz, K., Beaton-La Placa, D., Chen, S., Tukey, R. H., and Stevens, J. C. (2010) A humanized UGT1 mouse model expressing the UGT1A1*28 allele for assessing drug clearance by UGT1A1 dependent glucuronidation. Drug Metabol Dispos. 38(5), 879-86.

PubMedID: 20124398
PubMed Central ID: 

Vahisalu, T., Kollist, H., Wang, Y. F., Nishimura, N., Chan, W. Y., Valerio, G., Lamminmaki, A., Brosche, M., Moldau, H., Desikan, R., Schroeder, J. I., Kangasjarvi, J. (2008) SLAC1 is required for plant guard cell S‐type anion channel function in stomatal signalling. Nature. 452, 487‐91.

PubMedID: 18305484

Pages